| In Spite of Ourselves | ||||
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| Studio album by John Prine (with various accompanists) | ||||
| Released | September 28, 1999 | |||
| Recorded | August–October 1997, mid 1998, December 1998–99 | |||
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| Genre | Folk, alt-country, Americana | |||
| Length | 43:23 | |||
| Label | Oh Boy | |||
| Producer | Jim Rooney, John Prine | |||
| John Prine chronology | ||||
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In Spite of Ourselves is the 13th studio album of John Prine, featuring duets with various well-known female folk and alt-country vocalists, released in 1999.
The album was Prine's first release since successfully battling throat cancer. The female duet partners include Iris DeMent, Connie Smith, Lucinda Williams, Trisha Yearwood, Melba Montgomery, Emmylou Harris, Dolores Keane, Patty Loveless, and his wife, Fiona Prine.