Integrin alpha 9

ITGA9
Identifiers
Aliases	ITGA9, ALPHA-RLC, ITGA4L, RLC, integrin subunit alpha 9
External IDs	OMIM: 603963; MGI: 104756; HomoloGene: 1664; GeneCards: ITGA9; OMA:ITGA9 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	37,823,507 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	118,730,071 bp
RNA expression pattern
	Top expressed in
	urethra; ; saphenous vein; ; visceral pleura; ; right ventricle; ; Descending thoracic aorta; ; tendon of biceps brachii; ; vena cava; ; ascending aorta; ; thyroid gland; ; right lobe of thyroid gland;
	Top expressed in
	zygote; ; ascending aorta; ; secondary oocyte; ; primary oocyte; ; aortic valve; ; Gonadal ridge; ; external carotid artery; ; internal carotid artery; ; genital tubercle; ; interventricular septum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	metal ion binding; laminin binding; collagen binding;
Cellular component	integrin complex; basal plasma membrane; plasma membrane; membrane; integrin alpha9-beta1 complex; integral component of membrane;
Biological process	wound healing; integrin-mediated signaling pathway; extracellular matrix organization; neutrophil chemotaxis; cell adhesion;
	Sources:Amigo / QuickGO
Orthologs
	3680
	104099
	ENSG00000144668
	ENSMUSG00000039115
	Q13797
	B8JK39
	NM_002207
	NM_001113514; NM_133721
	NP_002198
	NP_001106986; NP_598482
	Wikidata
View/Edit Human	View/Edit Mouse

Integrin alpha-9 is a protein that in humans is encoded by the ITGA9 gene.^[5]^[6]^[7] Cytogenetic location: 3p22.2 ^[8]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000144668 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000039115 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Palmer EL, Rüegg C, Ferrando R, Pytela R, Sheppard D (Jan 1994). "Sequence and tissue distribution of the integrin alpha 9 subunit, a novel partner of beta 1 that is widely distributed in epithelia and muscle". J Cell Biol. 123 (5): 1289–97. doi:10.1083/jcb.123.5.1289. PMC 2119880. PMID 8245132.
^ Hibi K, Yamakawa K, Ueda R, Horio Y, Murata Y, Tamari M, Uchida K, Takahashi T, Nakamura Y, Takahashi T (Feb 1994). "Aberrant upregulation of a novel integrin alpha subunit gene at 3p21.3 in small cell lung cancer". Oncogene. 9 (2): 611–9. PMID 8290272.
^ "Entrez Gene: ITGA9 integrin, alpha 9".
^ Sulimova G, Kutsenko A, Rakhmanaliev E, Udina I, Kompaniytsev A, Protopopov A, Moisjak E, Klimov E, Muravenko O, Zelenin A, Braga E, Kashuba V, Zabarovsky E, Kisselev L (2002). "Human chromosome 3: integration of 60 NotI clones into a physical and gene map". Cytogenetic and Genome Research. 98 (2–3): 177–183. doi:10.1159/000069814. PMID 12698000. S2CID 41010053.