Integrin beta 5

ITGB5
Identifiers
Aliases	ITGB5, Integrin, beta 5, integrin subunit beta 5
External IDs	OMIM: 147561; MGI: 96614; HomoloGene: 20511; GeneCards: ITGB5; OMA:ITGB5 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	124,901,418 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	33,769,708 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; right coronary artery; ; ascending aorta; ; Descending thoracic aorta; ; pancreatic ductal cell; ; tendon of biceps brachii; ; cartilage tissue; ; left coronary artery; ; metanephric glomerulus; ; popliteal artery;
	Top expressed in
	tunica media of zone of aorta; ; epithelium of lens; ; decidua; ; calvaria; ; ciliary body; ; molar; ; external carotid artery; ; gastrula; ; stria vascularis; ; stroma of bone marrow;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	virus receptor activity; protein binding; integrin binding; signaling receptor activity;
Cellular component	integral component of membrane; membrane; focal adhesion; receptor complex; plasma membrane; cell surface; integrin complex; phagocytic vesicle; integrin alphav-beta5 complex; extracellular exosome;
Biological process	muscle contraction; endodermal cell differentiation; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; extracellular matrix organization; epithelial cell-cell adhesion; stress fiber assembly; cell adhesion; integrin-mediated signaling pathway; viral entry into host cell; cell-matrix adhesion; viral process; transforming growth factor beta receptor signaling pathway; cell migration; cell adhesion mediated by integrin;
	Sources:Amigo / QuickGO
Orthologs
	3693
	16419
	ENSG00000082781
	ENSMUSG00000022817
	P18084
	O70309
	NM_002213; NM_001354764; NM_001354765; NM_001354766
	NM_001145884; NM_010580
	NP_002204; NP_001341693; NP_001341694; NP_001341695
	NP_001139356; NP_034710; NP_001391992
	Wikidata
View/Edit Human	View/Edit Mouse

Integrin beta-5 is a protein that in humans is encoded by the ITGB5 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000082781 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022817 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ McLean JW, Vestal DJ, Cheresh DA, Bodary SC (Nov 1990). "cDNA sequence of the human integrin beta 5 subunit". J Biol Chem. 265 (28): 17126–31. doi:10.1016/S0021-9258(17)44878-2. PMID 2211615.
^ "Entrez Gene: ITGB5 integrin, beta 5".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000082781 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000022817 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid2211615-5] McLean JW, Vestal DJ, Cheresh DA, Bodary SC (Nov 1990). "cDNA sequence of the human integrin beta 5 subunit". J Biol Chem. 265 (28): 17126–31. doi:10.1016/S0021-9258(17)44878-2. PMID 2211615.

[entrez-6] "Entrez Gene: ITGB5 integrin, beta 5".

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