Skulltrail is an enthusiast gaming platform released by Intel on February 19, 2008. It is based on Intel's 5400 "Seaburg" workstation chipset. The primary difference between Skulltrail and Intel's current and past enthusiast chipsets is a dual CPU socket design that allows two processors to operate on the same motherboard. Therefore, Skulltrail can operate eight processing cores on one system. The platform supports two Core 2 Extreme QX9775 processors (commonly mistaken for the Core 2 Extreme QX9770, which is the LGA775 counterpart), which operate at 3.2 GHz.
Skulltrail was one of the first platforms to support SLI on chipsets not designed by Nvidia. It achieves this by including two NVIDIA nForce 100 PCIe 1.1 switch chips (two x16 to one x16). The implementation of SLI supports Quad SLI technology, which is achieved through the use of two dual-GPU graphics cards from NVIDIA, including the GeForce 9800 GX2. This gives a total of four graphics processors. Owners of Skulltrail systems can also make use of up to four ATI graphics cards using ATI CrossFireX technology, which made SkullTrail the only platform (other than Intel X58 and P55 Chipset) to support both SLI and CrossFire with public drivers at the time of release. The HP Firebird 803 also supported SLI on one (proprietary, MXM) motherboard at the time, but the drivers were special and only available for Firebird hardware.