Ionis Pharmaceuticals

Ionis Pharmaceuticals, Inc.
FormerlyIsis Pharmaceuticals, Inc.
Company typePublic
IndustryBiotechnology
Founded1989; 35 years ago (1989)
FounderStanley T. Crooke
HeadquartersCarlsbad, California, U.S.
Key people
Brett P. Monia (CEO)[1]
Elizabeth L. Hougen (CFO)[2]
Joseph Loscalzo
(chairman of the board)[3]
Productsnusinersen, inotersen, volanesorsen, plazomicin, mipomersen
RevenueDecrease US$587 million (2022)
Decrease US$−270 million (2022)
Total assetsDecrease US$2.53 billion (2022)
Total equityDecrease US$573 million (2022)
Number of employees
796 (December 2022)
Websiteionispharma.com
Footnotes / references
[4]

Ionis Pharmaceuticals, Inc. is a biotechnology company based in Carlsbad, California, that specializes in discovering and developing RNA-targeted therapeutics. The company has three commercially approved medicines: Spinraza (Nusinersen), Tegsedi (Inotersen), and Waylivra (Volanesorsen), and has four drugs in pivotal studies: tominersen for Huntington's disease (together with Roche), tofersen for SOD1-ALS, AKCEA-APO(a)-LRx for cardiovascular disease, and AKCEA-TTR-LRx for all forms of TTR amyloidosis.[4]

The company was named Isis Pharmaceuticals until December 2015.[5]

  1. ^ "Brett P Monia Chief Executive Officer/Co-Founder, Ionis Pharmaceuticals Inc". www.bloomberg.com. Retrieved 20 May 2022.
  2. ^ "Elizabeth L. Hougen Chief Financial Officer & Executive VP-Finance, Ionis Pharmaceuticals, Inc". www.wsj.com. Retrieved 20 May 2022.
  3. ^ "Ionis announces changes to its board of directors at annual meeting of stockholders". www.prnewswire.com (Press release). Retrieved 20 May 2022.
  4. ^ a b "Ionis Pharmaceuticals, Inc. 2022 Form 10-K Annual Report". U.S. Securities and Exchange Commission. February 22, 2023.
  5. ^ Fikes, Bradley (December 18, 2015). "From Isis Pharma to Ionis". The San Diego Union-Tribune.