Isaac Wilson may refer to:
- Isaac Wilson (physician) (1757–1844) English physician to Haslar Naval Hospital and Royal family
- Isaac Wilson (American politician), United States Representative from New York
- Isaac Wilson (English politician) (1822–1899), English industrialist and Liberal Party MP from Middlesbrough
- Isaac Wilson (New Zealand politician) (1840–1901), New Zealand MP
- Isaac Wilson (American football), American football player
This disambiguation page lists articles about people with the same name.
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