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| Isle Casino Hotel Bettendorf | |
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| Location | Bettendorf, Iowa |
| Address | 1777 Isle Pkwy |
| Opening date | April 21, 1995 |
| No. of rooms | 514 |
| Total gaming space | 35,000 sq ft (3,300 m2) |
| Casino type | Land-based |
| Owner | Caesars Entertainment |
| Previous names | Lady Luck Bettendorf Isle of Capri Bettendorf |
| Renovated in | 2016 |
| Coordinates | 41°31′10″N 90°32′33″W / 41.51944°N 90.54250°W |
| Website | IsleBettendorf.com |
Isle Casino Hotel Bettendorf is a casino hotel in Bettendorf, Iowa, owned and operated by Caesars Entertainment. It is one of several casinos located in the Quad Cities.