Isometamidium chloride

Isometamidium chloride
Clinical data
ATCvet code
Identifiers
  • 3-[N'-[(3-amino-5-ethyl-6-phenyl-8-phenanthridin-5-iumyl)imino]hydrazino]benzamidine chloride
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.047.191 Edit this at Wikidata
Chemical and physical data
FormulaC28H26ClN7
Molar mass496.02 g·mol−1
3D model (JSmol)
  • [Cl-].[N@H]=C(N)c1cc(ccc1)N/N=N/c4ccc3c2ccc(N)cc2[n+](c(c3c4)c5ccccc5)CC
  • InChI=1S/C28H25N7.ClH/c1-2-35-26-16-20(29)11-13-24(26)23-14-12-22(17-25(23)27(35)18-7-4-3-5-8-18)33-34-32-21-10-6-9-19(15-21)28(30)31;/h3-17,29H,2H2,1H3,(H4,30,31,32,33);1H
  • Key:QNZJTSGALAVCLH-UHFFFAOYSA-N

Isometamidium chloride is a triazene trypanocidal agent used in veterinary medicine.[1][2]

It consists of a single ethidium bromide like subunit linked to a fragment of the diminazene molecule.[citation needed]

  1. ^ Whitelaw DD, Bell IR, Holmes PH, Moloo SK, Hirumi H, Urquhart GM, Murray M (June 1986). "Isometamidium chloride prophylaxis against Trypanosoma congolense challenge and the development of immune responses in Boran cattle". The Veterinary Record. 118 (26): 722–6. doi:10.1136/vr.118.26.722 (inactive 1 November 2024). PMID 3739193. S2CID 39168151.{{cite journal}}: CS1 maint: DOI inactive as of November 2024 (link)
  2. ^ Peregrine AS, Ogunyemi O, Whitelaw DD, Holmes PH, Moloo SK, Hirumi H, et al. (April 1988). "Factors influencing the duration of isometamidium chloride (Samorin) prophylaxis against experimental challenge with metacyclic forms of Trypanosoma congolense". Veterinary Parasitology. 28 (1–2): 53–64. doi:10.1016/0304-4017(88)90018-0. PMID 3388736.