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Names | |||
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Preferred IUPAC name
1,2-Thiazole[1] | |||
Other names
isothiazole
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Identifiers | |||
3D model (JSmol)
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ChEBI | |||
ChemSpider | |||
ECHA InfoCard | 100.241.294 | ||
PubChem CID
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UNII | |||
CompTox Dashboard (EPA)
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Properties | |||
C3H3NS | |||
Molar mass | 85.12 g·mol−1 | ||
Boiling point | 114 °C (237 °F; 387 K)[3] | ||
Acidity (pKa) | -0.5 (of conjugate acid)[2] | ||
Related compounds | |||
Related compounds
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thiazole, isoxazole | ||
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Isothiazole, or 1,2-thiazole, is an organic compound consisting with the formula (CH)3S(N). The ring is unsaturated and features an S-N bond.[4] The isomeric thiazole, where the S and N are not directly bonded are far more common.
Isothiazones are produced by oxidation of enamine-thiones.[5] The ring structure of isothiazole is incorporated into larger compounds with biological activity such as the pharmaceutical drugs ziprasidone and perospirone.