Look up Ithaca in Wiktionary, the free dictionary.
Ithaca most commonly refers to:
- Homer's Ithaca, an island featured in Homer's Odyssey
- Ithaca (island), an island in Greece, possibly Homer's Ithaca
- Ithaca, New York, a city, and home of Cornell University and Ithaca College
Ithaca, Ithaka or Ithica may also refer to: