JAM3

JAM3
Identifiers
Aliases	JAM3, JAM-2, JAM-3, JAM-C, JAMC, junctional adhesion molecule 3
External IDs	OMIM: 606871; MGI: 1933825; HomoloGene: 11338; GeneCards: JAM3; OMA:JAM3 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	134,152,001 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	27,066,717 bp
RNA expression pattern
	Top expressed in
	corpus callosum; ; inferior ganglion of vagus nerve; ; ventricular zone; ; olfactory bulb; ; globus pallidus; ; internal globus pallidus; ; external globus pallidus; ; trigeminal ganglion; ; saphenous vein; ; subthalamic nucleus;
	Top expressed in
	sciatic nerve; ; ventricular zone; ; spermatocyte; ; lens; ; utricle; ; spermatid; ; extraocular muscle; ; neural tube; ; medial ganglionic eminence; ; epiblast;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein homodimerization activity; integrin binding; protein binding; protein heterodimerization activity;
Cellular component	integral component of membrane; membrane; cell-cell contact zone; cell-cell junction; bicellular tight junction; plasma membrane; desmosome; Schmidt-Lanterman incisure; extracellular region; cell junction; paranodal junction; extracellular space; Golgi apparatus; integral component of plasma membrane;
Biological process	neutrophil homeostasis; regulation of neutrophil chemotaxis; regulation of actin cytoskeleton organization by cell-cell adhesion; myeloid progenitor cell differentiation; adaptive immune response; axon regeneration; transmission of nerve impulse; leukocyte migration involved in inflammatory response; extracellular matrix organization; cell adhesion; angiogenesis; spermatogenesis; establishment of cell polarity; spermatid development; myelination; cell-matrix adhesion; cell migration; leukocyte migration; cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	83700
	83964
	ENSG00000166086
	ENSMUSG00000031990
	Q9BX67
	Q9D8B7
	NM_032801; NM_001205329
	NM_023277
	NP_001192258; NP_116190
	NP_075766
	Wikidata
View/Edit Human	View/Edit Mouse

Junctional adhesion molecule C is a protein that in humans is encoded by the JAM3 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000166086 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031990 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: JAM3 junctional adhesion molecule 3".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000166086 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031990 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: JAM3 junctional adhesion molecule 3".

[1]

[2]

[3]

[4]

[5]