James Andrews or Jim Andrews may refer to:
- James Andrews (botanical artist) (1801–1876), English botanical artist
- James J. Andrews (1829–1862), American Civil War spy
- James J. Andrews (mathematician) (1930–1998), American mathematician
- Sir James Andrews, 1st Baronet (1877–1951), member of Privy Council of Northern Ireland
- James Andrews (physician) (born 1942), American surgeon, renowned practitioner of sports medicine
- James Pettit Andrews (1737–1797), English historian and antiquary
- Jamie Andrews, fictional character from the drama series, Instant Star
- Jim Andrews (1865–1907), American baseball player
- Jim Andrews, owner of Andrews McMeel Universal
- James Andrews (musician) (born 1969), American musician
- James Andrews (stonemason) (1828–1897), Scottish-American stonemason and engineer
- James David Andrews (born 1992), American football player