Jay Frank Schamberg (November 6, 1870 – March 30, 1934) was a physician and prominent dermatologist/syphilogist in Philadelphia, PA during the first third of the twentieth century. He first became known as a strong advocate for smallpox vaccination prior to 1910.[1] He had two diseases named for him, one of which continues to carry his eponym. During World War I, Schamberg's research laboratory successfully synthesized Salvarsan, the standard treatment for syphilis, which had previously only been available from Germany.[2]