Jeremy R. Knowles

Jeremy Knowles
Born
Jeremy Randall Knowles

(1935-04-28)28 April 1935
Rugby, England[6]
Died3 April 2008(2008-04-03) (aged 72)
EducationBalliol College, Oxford (BA)
Merton College, Oxford (DPhil)
Known forEnzyme catalysis
AwardsWelch Award in Chemistry (1995)
Nakanishi Prize (1999)
Scientific career
FieldsBiochemistry
InstitutionsHarvard University
California Institute of Technology
ThesisIntramolecular effects in aromatic systems (1961)
Doctoral students
Other notable studentsLia Addadi[5]

Jeremy Randall Knowles CBE FRS (28 April 1935 – 3 April 2008) was a professor of chemistry at Harvard University who served as dean of the Harvard University faculty of arts and sciences (FAS) from 1991 to 2002.[8][9][10] He joined Harvard in 1974, received many awards for his research, and remained at Harvard until his death, leaving the faculty for a decade to serve as Dean. Knowles died on 3 April 2008 at his home.[7]

In 2006, he was selected by incoming interim president Derek Bok to return to his position as Dean of the Faculty of Arts and Sciences on an interim basis, replacing William C. Kirby.[11][12][13]

  1. ^ Bayley, H.; Knowles, J. R. (1978). "Photogenerated reagents for membrane labeling. 2. Phenylcarbene and adamantylidene formed within the lipid bilayer". Biochemistry. 17 (12): 2420–2423. doi:10.1021/bi00605a026. PMID 678520.
  2. ^ Buchwald, Stephen L.; Knowles, Jeremy R. (1982). "Nucleophilic displacements on phosphoric monoesters: Stereochemical evidence". Journal of the American Chemical Society. 104 (5): 1438–1440. doi:10.1021/ja00369a055.
  3. ^ Cornish-Bowden, A. J.; Knowles, J. R. (1969). "The pH-dependence of pepsin-catalysed reactions". Biochemical Journal. 113 (2): 353–362. doi:10.1042/bj1130353. PMC 1184642. PMID 4897198.
  4. ^ Raines, Ronald T.; Knowles, Jeremy R. (1987). "Enzyme relaxation in the reaction catalyzed by triosephosphate isomerase: Detection and kinetic characterization of two unliganded forms of the enzyme". Biochemistry. 26 (22): 7014–7020. doi:10.1021/bi00396a024. PMID 3427057.
  5. ^ Addadi, Lia; Jaffe, Eileen K.; Knowles, Jeremy R. (1983). "Secondary tritium isotope effects as probes of the enzymic and nonenzymic conversion of chorismate to prephenate". Biochemistry. 22 (19): 4494–4501. doi:10.1021/bi00288a022. PMID 6354259.
  6. ^ "Jeremy Randall Knowles". 14 May 2009.
  7. ^ a b Raines, R. T. (2008). "Jeremy R. Knowles (1935–2008)". ACS Chemical Biology. 3 (5): 262–264. doi:10.1021/cb800099n. PMID 18484705.
  8. ^ Bio from Harvard (from the office of news and public affairs)
  9. ^ "Public biography". Archived from the original on 30 December 2004. Retrieved 20 December 2005.
  10. ^ Harvard Crimson Profile
  11. ^ Jeremy R. Knowles named Interim Dean of the Faculty of Arts and Sciences Archived 17 May 2008 at the Wayback Machine, Harvard University Gazette, published 2006-05-22. Retrieved 2009-06-10.
  12. ^ "Harvard Gazette Obituary". Archived from the original on 11 May 2008. Retrieved 4 April 2008.
  13. ^ Daily Telegraph Obituary