John Fry may refer to:
- John Fry (16th century MP), MP for Lyme Regis
- John Fry (regicide) (1609–1657), English Member of Parliament and a judge at the trial of Charles I
- John Fry (record producer) (1944–2014), founder of Ardent Records
- John Fry (businessman) (born 1944), co-founder of Fry's Electronics
- John Fry (cricketer) (born 1961), former English cricketer
- John Wesley Fry (1876–1946), politician in Alberta, Canada and a former mayor of Edmonton
- John Anderson Fry (born 1960), president of Drexel University and former president of Franklin & Marshall College
- Johnny Fry (1840–1863), first "official" westbound rider of the Pony Express
- John Franklin Fry, character in Revolution (TV series)
- John Hemming Fry (1861–1946), American painter
- John Fry (journalist) (1930–2020), Canadian journalist specialized in outdoor recreation and travel