John Luke

John Luke may refer to:

• John A. Luke Jr., chief executive officer of MeadWestvaco
• John Luke (artist) (1906–1975), Irish artist
• John Luke (New Zealand politician) (1858–1931), New Zealand politician
• John Luke (MP) (1563–1638), English politician who sat in the House of Commons from 1610 to 1611
• John Luke (died 1452), MP for Dunwich (UK Parliament constituency)