John Komnenos Angelos Doukas Synadenos (Greek: Ἰωάννης Κομνηνός Ἄγγελος Δούκας Συναδηνός) was a Byzantine noble and military leader with the rank of megas stratopedarches during the reigns of Michael VIII Palaiologos (r. 1259–1282) and Andronikos II Palaiologos (r. 1282–1328).