Jurkat cells

Jurkat cells are an immortalized line of human T lymphocyte cells that are used to study acute T cell leukemia, T cell signaling, and the expression of various chemokine receptors susceptible to viral entry, particularly HIV.[1] Jurkat cells can produce interleukin 2, and are used in research involving the susceptibility of cancers to drugs and radiation.

  1. ^ Abraham, Robert; Weiss, Arthur (2004). "Jurkat T cells and development of the T-cell receptor signalling paradigm". Nature. 4 (4): 301–308. doi:10.1038/nri1330. PMID 15057788. S2CID 13253575.