KCNA6

KCNA6
Identifiers
Aliases	KCNA6, HBK2, KV1.6, PPP1R96, potassium voltage-gated channel subfamily A member 6
External IDs	OMIM: 176257; MGI: 96663; HomoloGene: 1684; GeneCards: KCNA6; OMA:KCNA6 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	4,813,318 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	126,717,637 bp
RNA expression pattern
	Top expressed in
	testicle; ; prefrontal cortex; ; islet of Langerhans; ; ventricular zone; ; Brodmann area 9; ; Achilles tendon; ; cingulate gyrus; ; right frontal lobe; ; anterior cingulate cortex; ; ganglionic eminence;
	Top expressed in
	dentate gyrus of hippocampal formation granule cell; ; lumbar spinal ganglion; ; medial dorsal nucleus; ; superior frontal gyrus; ; lateral hypothalamus; ; globus pallidus; ; primary visual cortex; ; medial vestibular nucleus; ; trigeminal ganglion; ; cerebellar cortex;
	More reference expression data
	n/a
Gene ontology
Molecular function	voltage-gated potassium channel activity; ion channel activity; potassium channel activity; delayed rectifier potassium channel activity; voltage-gated ion channel activity;
Cellular component	axon terminus; integral component of membrane; voltage-gated potassium channel complex; axon; plasma membrane; potassium channel complex; integral component of plasma membrane; membrane;
Biological process	potassium ion transport; regulation of ion transmembrane transport; protein homooligomerization; ion transport; transmembrane transport; potassium ion transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	3742
	16494
	ENSG00000151079
	ENSMUSG00000038077
	P17658
	Q61923
	NM_002235
	NM_013568
	NP_002226
	NP_038596
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium voltage-gated channel subfamily A member 6 also known as K_v1.6 is a protein that in humans is encoded by the KCNA6 gene.^[5] The protein encoded by this gene is a voltage-gated potassium channel subunit.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000151079 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000038077 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels" (PDF). Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000151079 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000038077 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid16382104-5] Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels" (PDF). Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

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