KCNB2

KCNB2
Identifiers
Aliases	KCNB2, KV2.2, potassium voltage-gated channel subfamily B member 2
External IDs	OMIM: 607738; MGI: 99632; HomoloGene: 31263; GeneCards: KCNB2; OMA:KCNB2 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	72,938,349 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	15,793,974 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; testicle; ; islet of Langerhans; ; ganglionic eminence; ; prefrontal cortex; ; Brodmann area 23; ; ventricular zone; ; dorsolateral prefrontal cortex; ; Brodmann area 9; ; entorhinal cortex;
	Top expressed in
	olfactory bulb; ; dentate gyrus of hippocampal formation granule cell; ; ganglionic eminence; ; neural tube; ; mesencephalon; ; hippocampus proper; ; ganglion of neuraxis; ; secondary oocyte; ; Cortex of frontal lobe; ; primary visual cortex;
	More reference expression data
	n/a
Gene ontology
Molecular function	potassium channel activity; delayed rectifier potassium channel activity; voltage-gated ion channel activity; ion channel activity; protein heterodimerization activity; voltage-gated potassium channel activity;
Cellular component	perikaryon; cell projection; membrane; voltage-gated potassium channel complex; plasma membrane; neuronal cell body membrane; dendrite; integral component of membrane; soma;
Biological process	regulation of smooth muscle contraction; regulation of ion transmembrane transport; ion transport; potassium ion transport; transmembrane transport; protein homooligomerization; potassium ion transmembrane transport; protein localization to plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	9312
	98741
	ENSG00000182674
	ENSMUSG00000092083
	Q92953
	A6H8H5
	NM_004770
	NM_001033195; NM_001098528
	NP_004761
	NP_001091998
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium voltage-gated channel subfamily B member 2 is a protein that in humans is encoded by the KCNB2 gene.^[5]^[6] The protein encoded by this gene is a voltage-gated potassium channel subunit.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000182674 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000092083 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b Schmalz F, Kinsella J, Koh SD, Vogalis F, Schneider A, Flynn ER, et al. (May 1998). "Molecular identification of a component of delayed rectifier current in gastrointestinal smooth muscles". The American Journal of Physiology. 274 (5): G901–G911. doi:10.1152/ajpgi.1998.274.5.G901. PMID 9612272.
^ ^a ^b Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, et al. (December 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacological Reviews. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000182674 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000092083 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9612272-5] Schmalz F, Kinsella J, Koh SD, Vogalis F, Schneider A, Flynn ER, et al. (May 1998). "Molecular identification of a component of delayed rectifier current in gastrointestinal smooth muscles". The American Journal of Physiology. 274 (5): G901–G911. doi:10.1152/ajpgi.1998.274.5.G901. PMID 9612272.

[pmid16382104-6] Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, et al. (December 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacological Reviews. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

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