KCNC3

KCNC3
Identifiers
Aliases	KCNC3, KSHIIID, KV3.3, SCA13, potassium voltage-gated channel subfamily C member 3
External IDs	OMIM: 176264; MGI: 96669; HomoloGene: 3650; GeneCards: KCNC3; OMA:KCNC3 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	50,333,515 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	44,604,754 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; cerebellar vermis; ; right hemisphere of cerebellum; ; left lobe of thyroid gland; ; right lobe of thyroid gland; ; vena cava; ; lateral nuclear group of thalamus; ; pons; ; inferior ganglion of vagus nerve; ; external globus pallidus;
	Top expressed in
	cerebellar cortex; ; dentate gyrus of hippocampal formation granule cell; ; superior frontal gyrus; ; aortic arch; ; pontine nuclei; ; cerebellar vermis; ; primary visual cortex; ; lobe of cerebellum; ; deep cerebellar nuclei; ; lumbar subsegment of spinal cord;
	More reference expression data
	n/a
Gene ontology
Molecular function	voltage-gated potassium channel activity; ion channel activity; potassium channel activity; voltage-gated ion channel activity; delayed rectifier potassium channel activity;
Cellular component	integral component of membrane; voltage-gated potassium channel complex; plasma membrane; membrane; cytoplasm; cytoskeleton; cell cortex; cell junction; axon; dendrite; dendritic spine membrane; presynaptic membrane; cell projection; perikaryon; synapse; dendrite membrane; neuronal cell body membrane; soma;
Biological process	potassium ion transport; regulation of ion transmembrane transport; protein homooligomerization; ion transport; protein tetramerization; transmembrane transport; potassium ion transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	3748
	16504
	ENSG00000131398
	ENSMUSG00000062785
	Q14003
	Q63959
	NM_004977; NM_001372305
	NM_001290682; NM_008422
	NP_004968; NP_001359234
NP_001277611; NP_001372554; NP_001372555; NP_001372556; NP_001372557;
	NP_001372558; NP_001372559; NP_001372560; NP_001372561; NP_001372562; NP_001372563; NP_001372564; NP_001372565; NP_001372566; NP_032448
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium voltage-gated channel, Shaw-related subfamily, member 3 also known as KCNC3 or K_v3.3 is a protein that in humans is encoded by the KCNC3.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000131398 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000062785 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ghanshani S, Pak M, McPherson JD, Strong M, Dethlefs B, Wasmuth JJ, Salkoff L, Gutman GA, Chandy KG (February 1992). "Genomic organization, nucleotide sequence, and cellular distribution of a Shaw-related potassium channel gene, Kv3.3, and mapping of Kv3.3 and Kv3.4 to human chromosomes 19 and 1". Genomics. 12 (2): 190–6. doi:10.1016/0888-7543(92)90365-Y. PMID 1740329.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000131398 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000062785 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1740329-5] Ghanshani S, Pak M, McPherson JD, Strong M, Dethlefs B, Wasmuth JJ, Salkoff L, Gutman GA, Chandy KG (February 1992). "Genomic organization, nucleotide sequence, and cellular distribution of a Shaw-related potassium channel gene, Kv3.3, and mapping of Kv3.3 and Kv3.4 to human chromosomes 19 and 1". Genomics. 12 (2): 190–6. doi:10.1016/0888-7543(92)90365-Y. PMID 1740329.

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