KCNH3

KCNH3
Identifiers
Aliases	KCNH3, BEC1, ELK2, Kv12.2, potassium voltage-gated channel subfamily H member 3
External IDs	OMIM: 604527; MGI: 1341723; HomoloGene: 32150; GeneCards: KCNH3; OMA:KCNH3 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	49,558,337 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	99,140,698 bp
RNA expression pattern
	Top expressed in
	right frontal lobe; ; Brodmann area 9; ; cingulate gyrus; ; anterior cingulate cortex; ; prefrontal cortex; ; amygdala; ; caudate nucleus; ; putamen; ; right uterine tube; ; nucleus accumbens;
	Top expressed in
	superior frontal gyrus; ; primary visual cortex; ; dentate gyrus of hippocampal formation granule cell; ; prefrontal cortex; ; Region I of hippocampus proper; ; olfactory tubercle; ; subiculum; ; piriform cortex; ; gastrula; ; ciliary body;
	More reference expression data
	n/a
Gene ontology
Molecular function	phosphorelay sensor kinase activity; protein binding; voltage-gated potassium channel activity; ion channel activity; potassium channel activity; voltage-gated ion channel activity;
Cellular component	intracellular anatomical structure; plasma membrane; integral component of membrane; membrane; integral component of plasma membrane;
Biological process	phosphorelay signal transduction system; signal transduction; regulation of ion transmembrane transport; regulation of membrane potential; potassium ion transmembrane transport; potassium ion transport; ion transport; transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	23416
	16512
	ENSG00000135519
	ENSMUSG00000037579
	Q9ULD8
	Q9WVJ0
	NM_001314030; NM_012284
	NM_010601
	NP_001300959; NP_036416
	NP_034731
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium voltage-gated channel subfamily H member 3 is a protein that in humans is encoded by the KCNH3 gene.^[5]^[6] The protein encoded by this gene is a voltage-gated potassium channel subunit.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000135519 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000037579 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b Miyake A, Mochizuki S, Yokoi H, Kohda M, Furuichi K (Sep 1999). "New ether-a-go-go K(+) channel family members localized in human telencephalon". J Biol Chem. 274 (35): 25018–25. doi:10.1074/jbc.274.35.25018. PMID 10455180.
^ ^a ^b Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000135519 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000037579 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10455180-5] Miyake A, Mochizuki S, Yokoi H, Kohda M, Furuichi K (Sep 1999). "New ether-a-go-go K(+) channel family members localized in human telencephalon". J Biol Chem. 274 (35): 25018–25. doi:10.1074/jbc.274.35.25018. PMID 10455180.

[pmid16382104-6] Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

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