KCNH6

KCNH6
Identifiers
Aliases	KCNH6, ERG-2, ERG2, HERG2, Kv11.2, hERG-2, potassium voltage-gated channel subfamily H member 6
External IDs	OMIM: 608168; MGI: 2684139; HomoloGene: 32740; GeneCards: KCNH6; OMA:KCNH6 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	63,548,977 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	106,034,549 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; gonad; ; human kidney; ; testicle; ; anterior pituitary; ; islet of Langerhans; ; jejunal mucosa; ; prostate; ; duodenum; ; renal medulla;
	Top expressed in
	islet of Langerhans; ; layer of retina; ; neural layer of retina; ; optic nerve; ; molecular layer of cerebellar cortex; ; epiblast; ; granular layer; ; embryo; ; Purkinje cell; ; inferior colliculi;
	More reference expression data
	n/a
Gene ontology
Molecular function	voltage-gated potassium channel activity; ion channel activity; potassium channel activity; voltage-gated ion channel activity;
Cellular component	integral component of membrane; plasma membrane; membrane; integral component of plasma membrane;
Biological process	regulation of membrane potential; potassium ion transport; regulation of ion transmembrane transport; ion transport; transmembrane transport; potassium ion transmembrane transport; regulation of heart rate by cardiac conduction;
	Sources:Amigo / QuickGO
Orthologs
	81033
	192775
	ENSG00000173826
	ENSMUSG00000001901
	Q9H252
	n/a
	NM_001278919; NM_001278920; NM_030779; NM_173092
	NM_001037712
	NP_001265848; NP_001265849; NP_110406; NP_775115
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium voltage-gated channel subfamily H member 6 is a protein that in humans is encoded by the KCNH6 gene.^[5] The protein encoded by this gene is a voltage-gated potassium channel subunit.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000173826 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000001901 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000173826 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000001901 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid16382104-5] Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

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