KCNJ14

KCNJ14
Identifiers
Aliases	KCNJ14, IRK4, KIR2.4, potassium voltage-gated channel subfamily J member 14, potassium inwardly rectifying channel subfamily J member 14
External IDs	OMIM: 603953; MGI: 2384820; HomoloGene: 27086; GeneCards: KCNJ14; OMA:KCNJ14 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	48,466,980 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	45,474,206 bp
RNA expression pattern
	Top expressed in
	putamen; ; stromal cell of endometrium; ; gastrocnemius muscle; ; skin of leg; ; primary visual cortex; ; ventricular zone; ; skin of abdomen; ; muscle of thigh; ; caudate nucleus; ; skeletal muscle tissue;
	Top expressed in
	layer of retina; ; neural layer of retina; ; anterior horn of spinal cord; ; eyelid; ; olfactory cortex; ; spinal ganglia; ; lower eyelid; ; amygdala; ; upper eyelid; ; trigeminal ganglion;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	voltage-gated ion channel activity; inward rectifier potassium channel activity;
Cellular component	integral component of membrane; voltage-gated potassium channel complex; soma; plasma membrane; dendrite; membrane;
Biological process	potassium ion transport; regulation of ion transmembrane transport; ion transport; potassium ion import across plasma membrane; cardiac conduction;
	Sources:Amigo / QuickGO
Orthologs
	3770
	211480
	ENSG00000182324
	ENSMUSG00000058743
	Q9UNX9
	Q8JZN3
	NM_170720; NM_013348
	NM_145963
	NP_037480
	NP_666075
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium inwardly-rectifying channel, subfamily J, member 14 (KCNJ14), also known as K_ir2.4, is a human gene.^[5]

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel, and probably has a role in controlling the excitability of motor neurons. Two transcript variants encoding the same protein have been found for this gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000182324 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000058743 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: KCNJ14 potassium inwardly-rectifying channel, subfamily J, member 14".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000182324 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000058743 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: KCNJ14 potassium inwardly-rectifying channel, subfamily J, member 14".

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