KCNMB1

KCNMB1
Identifiers
Aliases	KCNMB1, BKbeta1, K(VCA)beta, SLO-BETA, hbeta1, hslo-beta, k(VCA)beta-1, slo-beta-1, potassium calcium-activated channel subfamily M regulatory beta subunit 1
External IDs	OMIM: 603951; MGI: 1334203; HomoloGene: 3054; GeneCards: KCNMB1; OMA:KCNMB1 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	170,389,634 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	33,923,641 bp
RNA expression pattern
	Top expressed in
	tail of epididymis; ; popliteal artery; ; tibial arteries; ; right coronary artery; ; muscle layer of sigmoid colon; ; seminal vesicula; ; saphenous vein; ; thoracic aorta; ; ascending aorta; ; Descending thoracic aorta;
	Top expressed in
	lumbar spinal ganglion; ; ascending aorta; ; aortic valve; ; rib; ; sphenoid bone; ; Meckel's cartilage; ; tunica media of zone of aorta; ; humerus; ; fibula; ; scapula;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium-activated potassium channel activity; potassium channel regulator activity;
Cellular component	integral component of membrane; voltage-gated potassium channel complex; plasma membrane; membrane;
Biological process	detection of calcium ion; response to calcium ion; potassium ion transport; ion transport; chemical synaptic transmission; human ageing; cellular response to hypoxia; cellular response to bile acid; positive regulation of potassium ion transmembrane transport; cellular response to ethanol; potassium ion transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	3779
	16533
	ENSG00000145936
	ENSMUSG00000020155
	Q16558
	Q8CAE3
	NM_004137
	NM_031169
	NP_004128
	NP_112446
	Wikidata
View/Edit Human	View/Edit Mouse

Calcium-activated potassium channel subunit beta-1 is a protein that in humans is encoded by the KCNMB1 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000145936 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000020155 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Tseng-Crank J, Godinot N, Johansen TE, Ahring PK, Strøbaek D, Mertz R, Foster CD, Olesen SP, Reinhart PH (Aug 1996). "Cloning, expression, and distribution of a Ca(2+)-activated K+ channel beta-subunit from human brain". Proceedings of the National Academy of Sciences of the United States of America. 93 (17): 9200–5. Bibcode:1996PNAS...93.9200T. doi:10.1073/pnas.93.17.9200. PMC 38619. PMID 8799178.
^ Jiang Z, Wallner M, Meera P, Toro L (Jan 1999). "Human and rodent MaxiK channel beta-subunit genes: cloning and characterization". Genomics. 55 (1): 57–67. doi:10.1006/geno.1998.5627. PMID 9888999.
^ "Entrez Gene: KCNMB1 potassium large conductance calcium-activated channel, subfamily M, beta member 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000145936 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000020155 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8799178-5] Tseng-Crank J, Godinot N, Johansen TE, Ahring PK, Strøbaek D, Mertz R, Foster CD, Olesen SP, Reinhart PH (Aug 1996). "Cloning, expression, and distribution of a Ca(2+)-activated K+ channel beta-subunit from human brain". Proceedings of the National Academy of Sciences of the United States of America. 93 (17): 9200–5. Bibcode:1996PNAS...93.9200T. doi:10.1073/pnas.93.17.9200. PMC 38619. PMID 8799178.

[pmid9888999-6] Jiang Z, Wallner M, Meera P, Toro L (Jan 1999). "Human and rodent MaxiK channel beta-subunit genes: cloning and characterization". Genomics. 55 (1): 57–67. doi:10.1006/geno.1998.5627. PMID 9888999.

[entrez-7] "Entrez Gene: KCNMB1 potassium large conductance calcium-activated channel, subfamily M, beta member 1".

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