KCNN4

KCNN4
Identifiers
Aliases	KCNN4, IK1, IKCA1, KCA4, KCa3.1, SK4, hIKCa1, hKCa4, hSK4, IK, DHS2, potassium calcium-activated channel subfamily N member 4
External IDs	OMIM: 602754; MGI: 1277957; HomoloGene: 1696; GeneCards: KCNN4; OMA:KCNN4 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	43,780,976 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	24,086,115 bp
RNA expression pattern
	Top expressed in
	olfactory zone of nasal mucosa; ; parotid gland; ; minor salivary glands; ; mucosa of transverse colon; ; granulocyte; ; skin of leg; ; trachea; ; skin of abdomen; ; placenta; ; lymph node;
	Top expressed in
	parotid gland; ; Paneth cell; ; lacrimal gland; ; submandibular gland; ; fetal liver hematopoietic progenitor cell; ; crypt of lieberkuhn of small intestine; ; lumbar spinal ganglion; ; thymus; ; transitional epithelium of urinary bladder; ; lymph node;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; protein phosphatase binding; calcium-activated potassium channel activity; potassium channel activity; calmodulin binding; small conductance calcium-activated potassium channel activity; Intermediate conductance calcium-activated potassium channel activity;
Cellular component	integral component of membrane; membrane; voltage-gated potassium channel complex; plasma membrane; vesicle; soma; neuron projection;
Biological process	calcium ion transport; positive regulation of protein secretion; cell volume homeostasis; potassium ion transport; saliva secretion; ion transport; positive regulation of T cell receptor signaling pathway; immune system process; defense response; phospholipid translocation; stabilization of membrane potential; potassium ion transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	3783
	16534
	ENSG00000104783
	ENSMUSG00000054342
	O15554
	O89109
	NM_002250
	NM_001163510; NM_008433
	NP_002241
	NP_001156982; NP_032459
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4, also known as KCNN4, is a human gene encoding the K_Ca3.1 protein.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000104783 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000054342 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: KCNN4 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000104783 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000054342 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: KCNN4 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4".

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