KIRREL

KIRREL1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4OFD
Identifiers
Aliases	KIRREL1, NEPH1, KIRREL, kin of IRRE like (Drosophila), Kin of IRRE-like protein 1, kirre like nephrin family adhesion molecule 1, NPHS23
External IDs	OMIM: 607428; MGI: 1891396; HomoloGene: 10089; GeneCards: KIRREL1; OMA:KIRREL1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	158,100,262 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	87,082,054 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; right coronary artery; ; Descending thoracic aorta; ; popliteal artery; ; tibial arteries; ; ascending aorta; ; gallbladder; ; left coronary artery; ; left uterine tube; ; right ovary;
	Top expressed in
	calvaria; ; molar; ; umbilical cord; ; stroma of bone marrow; ; epithelium of lens; ; hand; ; body of femur; ; endothelial cell of lymphatic vessel; ; vas deferens; ; foot;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	myosin binding; protein binding;
Cellular component	dendritic shaft; integral component of membrane; perinuclear region of cytoplasm; membrane raft; plasma membrane; membrane; cell projection membrane; cell-cell junction;
Biological process	negative regulation of protein phosphorylation; excretion; positive regulation of actin filament polymerization; cell-cell adhesion;
	Sources:Amigo / QuickGO
Orthologs
	55243
	170643
	ENSG00000183853
	ENSMUSG00000041734
	Q96J84
	Q80W68
	NM_001286349; NM_018240
	NM_001170985; NM_130867; NM_001377046
	NP_001273278; NP_060710
	NP_001164456; NP_570937; NP_001363975
	Wikidata
View/Edit Human	View/Edit Mouse

Kin of IRRE-like protein 1, also known as NEPH1, is a protein that in humans is encoded by the KIRREL gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000183853 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000041734 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Sellin L, Huber TB, Gerke P, Quack I, Pavenstädt H, Walz G (Jan 2003). "NEPH1 defines a novel family of podocin interacting proteins". FASEB J. 17 (1): 115–7. doi:10.1096/fj.02-0242fje. PMID 12424224. S2CID 17732086.
^ "Entrez Gene: KIRREL kin of IRRE like (Drosophila)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000183853 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000041734 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12424224-5] Sellin L, Huber TB, Gerke P, Quack I, Pavenstädt H, Walz G (Jan 2003). "NEPH1 defines a novel family of podocin interacting proteins". FASEB J. 17 (1): 115–7. doi:10.1096/fj.02-0242fje. PMID 12424224. S2CID 17732086.

[entrez-6] "Entrez Gene: KIRREL kin of IRRE like (Drosophila)".

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