KLF14

KLF14
Identifiers
Aliases	KLF14, BTEB5, Kruppel-like factor 14, Kruppel like factor 14
External IDs	OMIM: 609393; MGI: 3577024; HomoloGene: 76469; GeneCards: KLF14; OMA:KLF14 - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q32.2 Start 130,730,697 bp[1] End 130,734,207 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 A3.3 Start 30,932,958 bp[2] End 30,936,013 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad testicle right adrenal cortex left adrenal gland left adrenal cortex muscle of thigh gastrocnemius muscle subcutaneous adipose tissue skeletal muscle tissue smooth muscle tissue Top expressed in pituitary gland yolk sac lumbar subsegment of spinal cord embryo umbilical cord internal carotid artery condyle epididymis fossa efferent ductule More reference expression data BioGPS n/a
Gene ontology Molecular function DNA binding metal ion binding nucleic acid binding DNA-binding transcription activator activity, RNA polymerase II-specific sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific chromatin binding Cellular component nucleus Biological process regulation of transcription, DNA-templated transcription, DNA-templated transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of sphingolipid mediated signaling pathway regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 136259 619665 Ensembl ENSG00000266265 ENSMUSG00000073209 UniProt Q8TD94 Q19A41 RefSeq (mRNA) NM_138693 NM_001135093 RefSeq (protein) NP_619638 NP_001128565 Location (UCSC) Chr 7: 130.73 – 130.73 Mb Chr 6: 30.93 – 30.94 Mb PubMed search [3] [4]
Wikidata
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Krüppel-like factor 14, also known as basic transcription element-binding protein 5 (BTEB5) is a protein that in humans is encoded by the KLF14 gene.^[5] The corresponding Klf14 mouse gene is known as Sp6.^[6]