Kalama (1817–1870) was a Queen Consort of Hawaii.
Kalama may also refer to:
- Kalama, Washington, a city in Cowlitz County, Washington
- Kalama Atoll, Hawaiian name for Johnston Atoll
- Kalama Sutta, a Buddhist scripture
- Kamalatmika/Kalama, a Hindu Goddess
- Kalama (bug), a genus of heteropteran bugs