Kaposi's sarcoma-associated herpesvirus

Human gammaherpesvirus 8
Kaposi's sarcoma
Virus classification Edit this classification
(unranked): Virus
Realm: Duplodnaviria
Kingdom: Heunggongvirae
Phylum: Peploviricota
Class: Herviviricetes
Order: Herpesvirales
Family: Orthoherpesviridae
Genus: Rhadinovirus
Species:
Human gammaherpesvirus 8

Kaposi's sarcoma-associated herpesvirus (KSHV) is the ninth known human herpesvirus; its formal name according to the International Committee on Taxonomy of Viruses (ICTV) is Human gammaherpesvirus 8, or HHV-8 in short.[1] Like other herpesviruses, its informal names are used interchangeably with its formal ICTV name. This virus causes Kaposi's sarcoma, a cancer commonly occurring in AIDS patients,[2] as well as primary effusion lymphoma,[3] HHV-8-associated multicentric Castleman's disease and KSHV inflammatory cytokine syndrome.[4] It is one of seven currently known human cancer viruses, or oncoviruses.[2] Even after many years since the discovery of KSHV/HHV8, there is no known cure for KSHV associated tumorigenesis.

  1. ^ "ICTV Master Species List 2018b.v2". International Committee on Taxonomy of Viruses. Archived from the original on March 30, 2019. Retrieved 13 June 2019.
  2. ^ a b Boshoff, C.; Weiss, R. (2002). "Aids-related malignancies". Nature Reviews Cancer. 2 (5): 373–382. doi:10.1038/nrc797. PMID 12044013. S2CID 13513517.
  3. ^ Cesarman, E.; Chang, Y.; Moore, P. S.; Said, J. W.; Knowles, D. M. (1995). "Kaposi's Sarcoma–Associated Herpesvirus-Like DNA Sequences in AIDS-Related Body-Cavity–Based Lymphomas". New England Journal of Medicine. 332 (18): 1186–1191. doi:10.1056/NEJM199505043321802. PMID 7700311.
  4. ^ Cite error: The named reference Goncalves2017 was invoked but never defined (see the help page).