Karl Barry Sharpless

Karl Barry Sharpless
Sharpless in 2018
Born
Karl Barry Sharpless

(1941-04-28) April 28, 1941 (age 83)
Philadelphia, Pennsylvania, U.S.
Alma materDartmouth College (BA)
Stanford University (MS, PhD)
Known for
Spouse
Jan Dueser
(m. 1965)
Awards
Scientific career
FieldsStereochemistry
Institutions
ThesisStudies of the Mechanism of Action of 2,3-oxidosqualene-lanosterol cyclase: Featuring Enzymic Cyclization of Modified Squalene Oxides (1968)
Doctoral advisorEugene van Tamelen
Doctoral studentsM.G. Finn
Other notable studentsUndergrads: Post-docs:

Karl Barry Sharpless (born April 28, 1941) is an American stereochemist. He is a two-time Nobel laureate in Chemistry known for his work on stereoselective reactions and click chemistry.

Sharpless was awarded half of the 2001 Nobel Prize in Chemistry "for his work on chirally catalysed oxidation reactions", and one third of the 2022 prize, jointly with Carolyn R. Bertozzi and Morten P. Meldal, "for the development of click chemistry and bioorthogonal chemistry".[1][2] Sharpless is the fifth person (in addition to two organizations) to have twice been awarded a Nobel prize, along with Marie Curie, John Bardeen, Linus Pauling and Frederick Sanger, and the third to have been awarded two prizes in the same discipline (after Bardeen and Sanger).

  1. ^ "The 2001 Nobel Prize in Chemistry" (Press release). Nobel Foundation. October 10, 2001. Retrieved January 17, 2024.
  2. ^ Cite error: The named reference nobelprize.2022 was invoked but never defined (see the help page).