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Karolina of Legnica-Brieg-Wohlau (German: Charlotte von Liegnitz-Brieg-Wohlau, Polish: Karolina Piastówna; 2 December 1652 in Brzeg – 24 December 1707 in Wrocław), was a Silesian noble, duchess of Legnica, Brzeg and Wołów and the last member of the Silesian Piasts dynasty. She was the eldest daughter of Christian, Duke of Brieg and Louise of Anhalt-Dessau (daughter of John Casimir, Prince of Anhalt-Dessau). After the death of her father, she married secretly without the knowledge of her mother on 14 July 1672 to Duke Frederick von Schleswig-Holstein-Sonderburg-Wiesenburg (b. 1651 – d. 1724) and also became the duchess of Schleswig-Holstein-Sonderburg-Wiesenburg.