Klebsiella granulomatis

Klebsiella granulomatis
Scientific classification Edit this classification
Domain: Bacteria
Phylum: Pseudomonadota
Class: Gammaproteobacteria
Order: Enterobacterales
Family: Enterobacteriaceae
Genus: Klebsiella
Species:
K. granulomatis
Binomial name
Klebsiella granulomatis
(Aragão and Vianna 1913) Carter et al. 1999

Klebsiella granulomatis is a Gram-negative, rod-shaped bacterium of the genus Klebsiella[1] known to cause the sexually transmitted infection granuloma inguinale (or donovanosis). It was formerly called Calymmatobacterium granulomatis.[2]

It is a non-motile aerobic bacillus with a non-sporulated capsule measuring 0.5 to 2.0 μm.[3][4] It is biochemically characterised by being as catalase-positive, phenylalanine deaminase-negative, citrate test-positive, and urease-positive.[5] Among its virulence factors are its capsule, endotoxins, siderophores, antimicrobial resistance and antigenic phase variation.[6]

  1. ^ Ryan KJ, Ray CG, eds. (2004). Sherris Medical Microbiology (4th ed.). McGraw Hill. p. 370. ISBN 978-0-8385-8529-0.
  2. ^ O'Farrell N (December 2002). "Donovanosis". Sexually Transmitted Infections. 78 (6): 452–7. doi:10.1136/sti.78.6.452. PMC 1758360. PMID 12473810.
  3. ^ Richens J (December 1991). "The diagnosis and treatment of donovanosis (granuloma inguinale)". Genitourinary Medicine. 67 (6): 441–52. doi:10.1136/sti.67.6.441. PMC 1194766. PMID 1774048.
  4. ^ Liverani CA, Lattuada D, Mangano S, Pignatari C, Puglia D, Monti E, Bolis G (August 2012). "Hypertrophic donavanosis in a young pregnant woman". Journal of Pediatric and Adolescent Gynecology. 25 (4): e81-3. doi:10.1016/j.jpag.2011.10.002. PMID 22840941.
  5. ^ Mesia JM, Jáuregui JS, Arias PP (May 2007). "Donovanosis, case report" (PDF). Revista Mexicana de Coloproctologí. 13: 59–65 – via medigraphic Artemisa en lÌnea.
  6. ^ Stoner BP (2018-01-01). "Klebsiella granulomatis: Granuloma Inguinale". In Long SS, Prober CG, Fischer M (eds.). Principles and Practice of Pediatric Infectious Diseases (fifth ed.). Elsevier. pp. 823–824.e1. doi:10.1016/b978-0-323-40181-4.00139-0. ISBN 978-0-323-40181-4.