Kobuvirus is a genus of viruses in the order Picornavirales, in the family Picornaviridae. Humans and cattle serve as natural hosts. There are six species in this genus. Diseases associated with this genus include: gastroenteritis.[1][2] The genus was named because of the virus particles' lumpy appearance by electron microscopy; "kobu" means "knob" in Japanese.[3]
Three species of the genus include Aichivirus A (formerly Aichi virus), Aichivirus B (formerly Bovine kobuvirus) and Aichivirus C (formerly Porcine kobuvirus) each possessing a single serotype. Canine kobuvirus belong to species Aichivirus A.[4] Aichi virus infects humans,[5][6] while bovine kobuvirus,[7] porcine kobuvirus[8][9] and canine kobuvirus, as suggested by their names, infects cattle, swine, dogs and cats.
In 2014 a novel caprine kobuvirus was characterised after isolation from a Korean black goat.[10]
Nucleic acid sequence analysis and RT-PCR are used prevalently as detection and genotyping methods of kobuvirus although, there are some other techniques such as EM, and ELISA.[11]
^Reuter G, Boros A, Pankovics P (January 2011). "Kobuviruses - a comprehensive review". Reviews in Medical Virology. 21 (1): 32–41. doi:10.1002/rmv.677. PMID21294214.
^Yamashita T, Kobayashi S, Sakae K, Nakata S, Chiba S, Ishihara Y, Isomura S (November 1991). "Isolation of cytopathic small round viruses with BS-C-1 cells from patients with gastroenteritis". The Journal of Infectious Diseases. 164 (5): 954–7. doi:10.1093/infdis/164.5.954. PMID1658159.
^Reuter G, Boldizsár A, Pankovics P (2009). "Complete nucleotide and amino acid sequences and genetic organization of porcine kobuvirus, a member of a new species in the genus Kobuvirus, family Picornaviridae". Archives of Virology. 154 (1): 101–8. doi:10.1007/s00705-008-0288-2. PMID19096904.
^Oem JK, Lee MH, Lee KK, An DJ (August 2014). "Novel Kobuvirus species identified from black goat with diarrhea". Veterinary Microbiology. 172 (3–4): 563–7. doi:10.1016/j.vetmic.2014.06.009. PMID24984842.