Konstantin Tretiakoff

Konstantin Tretiakoff
Konstantin Tretiakoff
BornDecember 26, 1892
Fergana, Uzbekistan
Died1958
NationalityRussian
Known forParkinson's disease
Scientific career
FieldsNeuropathology

Konstantin Nikolaevitch Tretiakoff (Russian: Константин Николаевич Третьяков; December 26, 1892 – 1958) was a Russian neuropathologist. He was born in Fergana, Uzbekistan, as a son of military physician, who was member of Pierre Bonvalot's first Pamir expedition. He studied medicine in L'Assistance Publique des Hopitaux de Paris. He received his doctorate in 1919. In his thesis, he described degeneration of the substantia nigra associated with paralysis agitans (Parkinson disease). Tretiakof was first to link this anatomic structure with parkinsonism. Between 1922 and 1926 Tretiakoff worked at the Hospício de Juquery, near the city of São Paulo, Brazil. In 1931, he was appointed Chairman at the new Department of Neuropathology at the Medical Institute in Saratov, USSR, where he spent the rest of his life.

In 1910, Fritz Heinrich Lewy discovered what became known as Lewy bodies,[1] and compared them to earlier findings by Gonzalo Rodríguez Lafora.[2] In 1913, Lafora described another case, and acknowledged Lewy as the discoverer, naming them cuerpos intracelulares de Lewy (Lewy bodies).[2] Trétiakoff found them in 1919 in the substantia nigra of PD brains, called them corps de Lewy and is credited with the eponym.[2] Eliasz Engelhardt argued in 2017 that Lafora should be credited with the eponym, because he named them six years before Trétiakoff.[3]

  1. ^ Hake MD, Ann Marie. "Dementia with Lewy bodies". MEDMERITS TM. Archived from the original on 2016-07-04.
  2. ^ a b c Engelhardt E (October 2017). "Lafora and Trétiakoff: the naming of the inclusion bodies discovered by Lewy" (PDF). Arq Neuropsiquiatr (Historical article). 75 (10): 751–753. doi:10.1590/0004-282X20170116. PMID 29166468.
  3. ^ Engelhardt E, Gomes M (2017). "Lewy and his inclusion bodies: Discovery and rejection". Dement Neuropsychol. 11 (2): 198–201. doi:10.1590/1980-57642016dn11-020012. PMC 5710688. PMID 29213511.