Kopexil

Kopexil
Names
IUPAC names
2,3-Dihydro-3-hydroxy-2-imino-4-pyrimidinamine
2,4-Diaminopyrimidine 3-N-oxide
Other names
Aminexil
Identifiers
3D model (JSmol)
ChemSpider
EC Number
  • 616-121-2
UNII
  • InChI=1S/C4H6N4O/c5-3-1-2-7-4(6)8(3)9/h1-2H,5H2,(H2,6,7)
    Key: SGHQFNHCCOBUKB-UHFFFAOYSA-N
  • InChI=1S/C4H6N4O/c5-3-1-2-7-4(6)8(3)9/h1-2,6,9H,5H2
    Key: YTKGAYFHUZTLCI-UHFFFAOYSA-N
  • c1cnc([n+](c1N)[O-])N
Properties
C4H6N4O
Molar mass 126.119 g·mol−1
Appearance white odorless crystals[1]
Melting point 210 to 218 °C (410 to 424 °F; 483 to 491 K)[1]
slightly soluble[1]
Hazards
GHS labelling:
GHS07: Exclamation mark
Warning
H302
P264, P270, P301+P312, P330, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Kopexil (INCI name diaminopyrimidine oxide, trade name Aminexil) is a chemical compound similar to minoxidil. Minoxidil was originally used to treat high blood pressure; a side effect was increased body hair. Both compounds have been used for therapy of alopecia.[2] Kopexil is not approved for use as a drug in the United States or in Europe.

  1. ^ a b c MSDS for Kopexil at Kumar Organics. Archived 2015-07-22 at the Wayback Machine March 28th 2012.
  2. ^ Trüeb RM, de Viragh PA: Status of scalp hair and therapy of alopecia in men in Switzerland; PMID 11256223.