Kubo or KUBO may refer to:
- Kubo (surname)
- Kubo gap, the average spacing between consecutive energy levels
- Kantō kubō, the ruler of the Kantō region during the early Muromachi period in Japan
- Lit Kubo, a proposed electric cargo scooter
- KUBO, a radio station in Calexico, California, U.S.
- Takefusa Kubo (born 2001), a Japanese footballer
- Tite Kubo, a Japanese manga author and artist best known for Bleach