LILRA5

LILRA5
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2D3V
Identifiers
Aliases	LILRA5, CD85, CD85F, ILT-11, ILT11, LILRB7, LIR-9, LIR9, leukocyte immunoglobulin like receptor A5
External IDs	OMIM: 606047; MGI: 3647196; HomoloGene: 83297; GeneCards: LILRA5; OMA:LILRA5 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	54,313,166 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	4,246,462 bp
RNA expression pattern
	Top expressed in
	blood; ; monocyte; ; granulocyte; ; spleen; ; bone marrow; ; bone marrow cells; ; appendix; ; right lung; ; upper lobe of left lung; ; testicle;
	Top expressed in
	trigeminal ganglion; ; spinal ganglia; ; liver; ; adrenal gland; ; jejunum; ; spleen; ; ileum; ; lung; ; right kidney; ; spinal cord;
	More reference expression data
	n/a
Orthologs
	353514
	232801
ENSG00000274113; ENSG00000274914; ENSG00000275404; ENSG00000187116; ENSG00000278355;
	n/a
	ENSMUSG00000070873
	A6NI73
	D3Z7A9
	NM_181986; NM_021250; NM_181879; NM_181985
	NM_001081239
	NP_067073; NP_870994; NP_871714; NP_871715
	NP_001074708
	Wikidata
View/Edit Human	View/Edit Mouse

Leukocyte immunoglobulin-like receptor subfamily A member 5 (LILR-A5) also known as CD85 antigen-like family member F (CD85f), immunoglobulin-like transcript 11 (ILT-11), and leukocyte immunoglobulin-like receptor 9 (LIR-9) is a protein that in humans is encoded by the LILRA5 gene.^[5]^[6]^[7] This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4.^[8] Four alternatively spliced transcript variants encoding distinct isoforms have been described.

^ ^a ^b ^c ENSG00000274914, ENSG00000275404, ENSG00000187116, ENSG00000278355 GRCh38: Ensembl release 89: ENSG00000274113, ENSG00000274914, ENSG00000275404, ENSG00000187116, ENSG00000278355 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000070873 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lao K, Zhang R, Dai Y, Luan J, Guo N, Xu X, et al. (July 2021). "Identification of novel Aβ-LilrB2 inhibitors as potential therapeutic agents for Alzheimer's disease". Molecular and Cellular Neurosciences. 114: 103630. doi:10.1016/j.mcn.2021.103630. PMID 34029694. S2CID 235203153.
^ "LILRA5 Gene - Leukocyte Immunoglobulin Like Receptor A5". Gene Cards. Retrieved 2021-12-11.
^ "LILRA5 leukocyte immunoglobulin like receptor A5 [Homo sapiens (human)]". Gene - NCBI. National Center for Biotechnology Information, U.S. National Library of Medicine. Retrieved 2021-12-11.
^ Torkar M, Haude A, Milne S, Beck S, Trowsdale J, Wilson MJ (December 2000). "Arrangement of the ILT gene cluster: a common null allele of the ILT6 gene results from a 6.7-kbp deletion". European Journal of Immunology. 30 (12): 3655–3662. doi:10.1002/1521-4141(200012)30:12<3655::AID-IMMU3655>3.0.CO;2-Y. PMID 11169408. S2CID 38450831.

[refGRCh38Ensembl-1] ENSG00000274914, ENSG00000275404, ENSG00000187116, ENSG00000278355 GRCh38: Ensembl release 89: ENSG00000274113, ENSG00000274914, ENSG00000275404, ENSG00000187116, ENSG00000278355 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000070873 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[Lao_103630-5] Lao K, Zhang R, Dai Y, Luan J, Guo N, Xu X, et al. (July 2021). "Identification of novel Aβ-LilrB2 inhibitors as potential therapeutic agents for Alzheimer's disease". Molecular and Cellular Neurosciences. 114: 103630. doi:10.1016/j.mcn.2021.103630. PMID 34029694. S2CID 235203153.

[6] "LILRA5 Gene - Leukocyte Immunoglobulin Like Receptor A5". Gene Cards. Retrieved 2021-12-11.

[7] "LILRA5 leukocyte immunoglobulin like receptor A5 [Homo sapiens (human)]". Gene - NCBI. National Center for Biotechnology Information, U.S. National Library of Medicine. Retrieved 2021-12-11.

[8] Torkar M, Haude A, Milne S, Beck S, Trowsdale J, Wilson MJ (December 2000). "Arrangement of the ILT gene cluster: a common null allele of the ILT6 gene results from a 6.7-kbp deletion". European Journal of Immunology. 30 (12): 3655–3662. doi:10.1002/1521-4141(200012)30:12<3655::AID-IMMU3655>3.0.CO;2-Y. PMID 11169408. S2CID 38450831.

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