Protein-coding gene in the species Homo sapiens
LRP6 Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3S2K , 3S8V , 3S8Z , 3S94 , 3SOB , 3SOQ , 3SOV , 4A0P , 4DG6 , 4NM5 , 4NM7
Identifiers Aliases LRP6 , ADCAD2, STHAG7, LDL receptor related protein 6External IDs OMIM : 603507 ; MGI : 1298218 ; HomoloGene : 1747 ; GeneCards : LRP6 ; OMA :LRP6 - orthologs Wikidata
Low-density lipoprotein receptor-related protein 6 is a protein that in humans is encoded by the LRP6 gene .[ 5] [ 6] LRP6 is a key component of the LRP5 /LRP6/Frizzled co-receptor group that is involved in canonical Wnt pathway .
^ a b c ENSG00000281324 GRCh38: Ensembl release 89: ENSG00000070018, ENSG00000281324 – Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030201 – Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Brown SD, Twells RC, Hey PJ, Cox RD, Levy ER, Soderman AR, Metzker ML, Caskey CT, Todd JA, Hess JF (1998). "Isolation and characterization of LRP6, a novel member of the low density lipoprotein receptor gene family". Biochem. Biophys. Res. Commun . 248 (3): 879–88. doi :10.1006/bbrc.1998.9061 . PMID 9704021 .
^ "Entrez Gene: LRP6 low density lipoprotein receptor-related protein 6" .