Ladderane

Simple ladderane structure

In chemistry, a ladderane is an organic molecule containing two or more fused cyclobutane rings. The name arises from the resemblance of a series of fused cyclobutane rings to a ladder. Numerous synthetic approaches have been developed for the synthesis of ladderane compounds of various lengths.[1] The mechanisms often involve [2 + 2] photocycloadditions, a useful reaction for creating strained 4-membered rings. Naturally occurring ladderanes have been identified as major components of the anammoxosome membrane of the anammox bacteria, phylum Planctomycetota.[2]

  1. ^ Hopf, Henning; Joel F. Liebman; H. Mark Perks (2009). "Cubanes, fenestranes, ladderanes, prismanes, staffanes and other oligocyclobutanoids". Patai's Chemistry of Functional Groups. doi:10.1002/9780470682531.pat0337. ISBN 9780470682531.
  2. ^ Fuerst, John A. (23 May 2005). "Intracellular Compartmentation in Planctomycetes". Annual Review of Microbiology. 59: 299–328. doi:10.1146/annurev.micro.59.030804.121258. PMID 15910279.