Sir Laurence Esmonde, 1st Baron Esmonde (1570?–1646), was an Irish peer who held office as governor of the fort of Duncannon in County Wexford. He was a leading Irish Royalist commander in the English Civil War, but was later suspected of disloyalty to the English Crown when he surrendered Duncannon Fort to the enemy. He was the ancestor of the Esmonde Baronets, although the barony died with him.