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| Lentivirus | |
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Virus classification 
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| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Pararnavirae |
| Phylum: | Artverviricota |
| Class: | Revtraviricetes |
| Order: | Ortervirales |
| Family: | Retroviridae |
| Subfamily: | Orthoretrovirinae |
| Genus: | Lentivirus |
| Species | |
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Lentivirus is a genus of retroviruses that cause chronic and deadly diseases characterized by long incubation periods, in humans and other mammalian species.[2] The genus includes the human immunodeficiency virus (HIV), which causes AIDS. Lentiviruses are distributed worldwide, and are known to be hosted in apes, cows, goats, horses, cats, and sheep as well as several other mammals.[2]
Lentiviruses can integrate a significant amount of viral complementary DNA into the DNA of the host cell and can efficiently infect nondividing cells, so they are one of the most efficient methods of gene delivery.[3] They can become endogenous, integrating their genome into the host germline genome, so that the virus is henceforth inherited by the host's descendants.[1]
- ^ a b Kambol, R; Gatseva, A; Gifford, RJ (20 December 2022). "An endogenous lentivirus in the germline of a rodent". Retrovirology. 19 (1): 30. doi:10.1186/s12977-022-00615-2. PMC 9768972. PMID 36539757.
- ^ a b "What is Lentivirus?". News-Medical.net. 2010-05-19. Retrieved 2015-11-30.
- ^ Cockrell, Adam S.; Kafri, Tal (2007-07-01). "Gene delivery by lentivirus vectors". Molecular Biotechnology. 36 (3): 184–204. doi:10.1007/s12033-007-0010-8. ISSN 1073-6085. PMID 17873406. S2CID 25410405.