Lipoblastomatosis

Benign lipoblastomatosis is a tumor consisting of fetal-embryonal adipocytes, frequently confused with a liposarcoma, affecting exclusively infants and young children, with approximately 90% of cases occurring before 3 years of age.^{[2][3]: 626} The term lipoblastomatosis was first used by Vellios et al. in 1958, at which point the tumor became generally accepted as a distinctive entity.^[4][5] Today Diffuse lipoblastoma is the preferred term for lipoblastomatosis.^[6][7] The tumor is rare, accounting for less than 1% of all childhood neoplasm,^[8] and it has been found to be more common in males than females.^[9][8] It often presents as an asymptomatic rapidly enlarging mass, occurring more often in the soft tissues of the extremities.^[8][9]