| Lithospermum erythrorhizon | |
|---|---|
| |
| Leaves | |
Scientific classification 
| |
| Kingdom: | Plantae |
| Clade: | Tracheophytes |
| Clade: | Angiosperms |
| Clade: | Eudicots |
| Clade: | Asterids |
| Order: | Boraginales |
| Family: | Boraginaceae |
| Genus: | Lithospermum |
| Species: | L. erythrorhizon
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| Binomial name | |
| Lithospermum erythrorhizon Siebold & Zucc. 1846
| |
Lithospermum erythrorhizon, commonly called purple gromwell, red stoneroot, red gromwell, red-root gromwell and redroot lithospermum, is a plant species in the family Boraginaceae.[1] It is called zǐcǎo (紫草) in Chinese, jichi (지치) in Korean, and murasaki (ムラサキ; 紫) in Japanese.[1]
The dried root of Lithospermum erythrorhizon (lithospermum root or Lithospermi Radix) is a Chinese herbal medicine with various antiviral and biological activities, including inhibition of human immunodeficiency virus type 1 (HIV-1).[2][3]
The genome of Lithospermum erythrorhizon has been sequenced and has facilitated the discovery of a putative retrotransposition-derived duplication event that produced a 4-hydroxybenzoate geranyltransferase gene involved in alkannin biosynthesis.[4]
- ^ a b "Lithospermum erythrorhizon". Germplasm Resources Information Network. Agricultural Research Service, United States Department of Agriculture.
- ^ Chen, X., et al. (2003). Shikonin, a component of Chinese herbal medicine, inhibits chemokine receptor function and suppresses human immunodeficiency virus type 1. Antimicrobial Agents and Chemotherapy 47(9), 2810-16.
- ^ Gao, H., et al. (2011). Anti-adenovirus activities of shikonin, a component of Chinese herbal medicine in vitro. Biol Pharm Bull. 34(2) 197-202.
- ^ Auber, Robert P.; Suttiyut, Thiti; McCoy, Rachel M.; et al. (2020-06-01). "Hybrid de novo genome assembly of red gromwell (Lithospermum erythrorhizon) reveals evolutionary insight into shikonin biosynthesis". Horticulture Research. 7 (1): 82. Bibcode:2020HorR....7...82A. doi:10.1038/s41438-020-0301-9. PMC 7261806. PMID 32528694.