Loewe additivity

In toxicodynamics and pharmacodynamics, Loewe additivity (or dose additivity) is one of several common reference models used for measuring the effects of drug combinations.[1][2][3]

  1. ^ Greco, W.R.; Bravo, G.; Parsons, J. (1995). "The Search for Synergy: A Critical Review from a Response Surface Perspective". Pharmacol. Rev. 47 (2): 331–385. PMID 7568331.
  2. ^ Loewe, S. (1926). "Effect of combinations: mathematical basis of problem". Arch. Exp. Pathol. Pharmakol. 114: 313–326. doi:10.1007/BF01952257. S2CID 19783017.
  3. ^ Tang, J.; Wennerberg, J.K.; Aittokallio, T. (2015). "What Is Synergy? The Saariselkä Agreement Revisited". Frontiers in Pharmacology. 6: 181. doi:10.3389/fphar.2015.00181. PMC 4555011. PMID 26388771.