Loricrin

LORICRIN
Identifiers
Aliases	LORICRIN, loricrin, LOR, loricrin cornified envelope precursor protein
External IDs	OMIM: 152445; GeneCards: LORICRIN; OMA:LORICRIN - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	153,262,124 bp
RNA expression pattern
	Top expressed in
	skin of arm; ; skin of thigh; ; nipple; ; vulva; ; human penis; ; skin of hip; ; skin of abdomen; ; gums; ; gingival epithelium; ; amniotic fluid;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein-macromolecule adaptor activity; structural constituent of cytoskeleton; protein binding; structural molecule activity; structural constituent of skin epidermis;
Cellular component	cytoplasm; nucleoplasm; nucleus; cornified envelope; cytosol;
Biological process	peptide cross-linking; keratinization; keratinocyte differentiation; cytoskeleton organization; cornification;
	Sources:Amigo / QuickGO
Orthologs
	4014
	n/a
	ENSG00000203782
	n/a
	P23490
	n/a
	NM_000427
	n/a
	NP_000418
	n/a
	Wikidata
View/Edit Human

Loricrin is a protein that in humans is encoded by the LOR gene.^[3]^[4]^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000203782 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Hohl D, Mehrel T, Lichti U, Turner ML, Roop DR, Steinert PM (May 1991). "Characterization of human loricrin. Structure and function of a new class of epidermal cell envelope proteins". J Biol Chem. 266 (10): 6626–36. doi:10.1016/S0021-9258(18)38163-8. PMID 2007607.
^ Yoneda K, Hohl D, McBride OW, Wang M, Cehrs KU, Idler WW, Steinert PM (Oct 1992). "The human loricrin gene". J Biol Chem. 267 (25): 18060–6. doi:10.1016/S0021-9258(19)37152-2. PMID 1355480.
^ "Entrez Gene: LOR loricrin".