Flavius Lupicinus was a Roman military commander in the 4th century AD. He was appointed magister equitum in 357, but fell out of favour when he refused to side with Julian when the army declared him Augustus. After Julian's death, he was appointed magister equitum per orientes in 363. In 365, he was the senior commander in the emperor Valens' campaign against the usurper Procopius, and following the defeat of Procopius was made consul in 367.