Luteinizing hormone beta polypeptide

LHB
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1M92
Identifiers
Aliases	LHB, CGB4, LSH-B, hHH23, Luteinizing hormone beta polypeptide, LSH-beta, Luteinizing hormone subunit beta
External IDs	OMIM: 152780; MGI: 96782; HomoloGene: 81806; GeneCards: LHB; OMA:LHB - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	49,017,091 bp
RNA expression pattern
	Top expressed in
	anterior pituitary; ; gonad; ; testicle; ; body of pancreas; ; endothelial cell; ; left testis; ; placenta; ; right testis; ; stromal cell of endometrium; ; body of stomach;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	signaling receptor binding; hormone activity;
Cellular component	Golgi lumen; extracellular region; extracellular space; cytoplasm;
Biological process	cell-cell signaling; progesterone biosynthetic process; male gonad development; peptide hormone processing; signal transduction; hormone-mediated signaling pathway; ovulation; regulation of signaling receptor activity; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	3972
	16866
	ENSG00000104826
	ENSMUSG00000100916
	P01229
	O09108
	NM_000894
	NM_008497
	NP_000885
	NP_032523
	Wikidata
View/Edit Human	View/Edit Mouse

Luteinizing hormone subunit beta also known as lutropin subunit beta or LHβ is a polypeptide that in association with an alpha subunit common to all gonadotropin hormones forms the reproductive signaling molecule luteinizing hormone. In humans it is encoded by the LHB gene.^[4]^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000104826 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Sairam MR, Li CH (Feb 1976). "Human pituitary lutropin. Isolation, properties, and the complete amino acid sequence of the beta-subunit". Biochim Biophys Acta. 412 (1): 70–81. doi:10.1016/0005-2795(75)90340-2. PMID 1191677.
^ "Entrez Gene: LHB luteinizing hormone beta polypeptide".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000104826 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1191677-4] Sairam MR, Li CH (Feb 1976). "Human pituitary lutropin. Isolation, properties, and the complete amino acid sequence of the beta-subunit". Biochim Biophys Acta. 412 (1): 70–81. doi:10.1016/0005-2795(75)90340-2. PMID 1191677.

[entrez-5] "Entrez Gene: LHB luteinizing hormone beta polypeptide".

[1]

[2]

[3]

[4]

[5]