State highway in Cass and St. Joseph counties in Michigan, United States
M-216 is a state trunkline highway in the US state of Michigan that serves as a connector route between M-40 at Marcellus and US Highway 131 (US 131). The highway runs through a rural area of the southwestern part of the state. It has been a part of the highway system since 1935; the current form of the roadway was finalized in 1939. Between 2,400 and 3,900 vehicles use the highway each day on average.
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