MAP3K9

MAP3K9
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3DTC, 4UY9
Identifiers
Aliases	MAP3K9, MEKK9, MLK1, PRKE1, mitogen-activated protein kinase kinase kinase 9
External IDs	OMIM: 600136; MGI: 2449952; HomoloGene: 76377; GeneCards: MAP3K9; OMA:MAP3K9 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	70,809,534 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	81,827,949 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; lateral nuclear group of thalamus; ; cerebellar vermis; ; pars compacta; ; frontal pole; ; postcentral gyrus; ; amniotic fluid; ; pars reticulata; ; orbitofrontal cortex; ; middle temporal gyrus;
	Top expressed in
	granulocyte; ; primary visual cortex; ; superior frontal gyrus; ; lip; ; dentate gyrus of hippocampal formation granule cell; ; esophagus; ; zygote; ; cerebellar cortex; ; neural layer of retina; ; ventricular zone;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; protein homodimerization activity; kinase activity; protein serine/threonine kinase activity; protein binding; ATP binding; MAP kinase kinase kinase activity; MAP kinase kinase activity; JUN kinase kinase kinase activity;
Cellular component	cytoplasm; cellular component; intracellular anatomical structure;
Biological process	regulation of transcription, DNA-templated; phosphorylation; cell death; transcription, DNA-templated; protein phosphorylation; positive regulation of apoptotic process; protein autophosphorylation; apoptotic process; MAPK cascade;
	Sources:Amigo / QuickGO
Orthologs
	4293
	338372
	ENSG00000006432
	ENSMUSG00000042724
	P80192
	Q3U1V8
	NM_001284230; NM_001284231; NM_001284232; NM_033141
	NM_001174107; NM_177395
	NP_001271159; NP_001271160; NP_001271161; NP_149132
	NP_001167578; NP_796369
	Wikidata
View/Edit Human	View/Edit Mouse

Mitogen-activated protein kinase kinase kinase 9 is an enzyme that in humans is encoded by the MAP3K9 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000006432 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000042724 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: MAP3K9 mitogen-activated protein kinase kinase kinase 9".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000006432 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000042724 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: MAP3K9 mitogen-activated protein kinase kinase kinase 9".

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